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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Novel genome-wide DNA methylation profiling reveals distinct epigenetic landscape, prognostic model and cellular composition of early-stage lung adenocarcinoma

Fig. 1

Global DNA methylation profile in early-stage LUAD. (A) Venn diagram displaying CpG sites (filtered for sex chromosomes and sequencing depth) measured by EM-seq(green) and 450K(brown). (B) Comparison of median CpG methylation levels between tumor and normal samples in EM-seq(left) and 450K(right). (C) Box plots displaying the methylation levels of each normal (light green) and tumor (bottle green) sample in EM-seq.  (D) Box plots displaying the methylation levels of each normal (pink) and tumor (café) sample in 450K. P values computed from Wilcoxon tests. EM-seq, n = 23; 450K, n = 15

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Journal of Translational Medicine

ISSN: 1479-5876

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