Fig. 1

Workflow chart of the study, created with BioRender. Abbreviations: BM, basement membrane; CNV, copy number variable; GO, Gene Ontology; EMT, epithelial-mesenchymal transition; GSEA, gene set enrichment analysis; ICGC, International Cancer Genome Consortium; ITGA3, integrin subunit alpha 3; KEGG, Kyoto Encyclopedia of Genes and Genomes; MBRGs, metastasis and basement membrane-related genes; PCA, principal component analysis; ROC, receiver operating characteristic; ssGSEA, single-sample gene set enrichment analysis; TCGA, The Cancer Genome Atlas; TIDE, tumor immune dysfunction and exclusion; TMB, tumor mutation burden; t-SNE, t-distributed stochastic neighbor embedding