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Table 5 Comparison of peripheral blood cytokine levels in drug-resistant epilepsy, drug-responsive epilepsy, drug-naïve epilepsy, and healthy controls

From: The correlation of GluR3B antibody with T lymphocyte subsets and inflammatory factors and their role in the progression of epilepsy

 

units

Drug-resistant patients (n = 64)

Drug-responsive patients (n = 41)

Drug-naïve patients (n = 66)

Healthy control (n = 40)

P

IL-1β [M (P25,P75)]

pg/ml

6.4 (2.5,9.7)

4.7 (1.6,8.2)

4.3 (1.3,8.3)

2.8 (2.1,6.6)

0.069

IL-2 [M (P25,P75)]

pg/ml

2.1 (1.0, 36.4)

1.7 (1.0, 3.2)

1.6 (0.8, 11.2)

1.7 (1.3, 2.5)

0.28

IL-4 [M (P25,P75)]

pg/ml

1.4 (0.8,10.0)

1.2 (0.9,2.7)

1.3 (0.8,4.0)

1.0 (0.9,2.6)

0.44

IL-5 [M (P25,P75)]

pg/ml

2.6 (1.5, 4.3)

2.5 (1.2, 5.8)

1.9 (1.1, 4.3)

2.4 (1.2, 3.1)

0.12

IL-6 [M (P25,P75)]

pg/ml

2.6 (1.6, 4.6)

3.0 (2.1, 6.1)

2.4 (1.4, 4.9)

2.3 (1.6, 3.8)

0.31

IL-8 [M (P25,P75)]

pg/ml

7.4 (2.5, 12.6)

1.4 (0.4, 4.8)

3.1 (0.8, 8.1)

1.0 (0.6, 2.4)

< 0.0001

IL-10 [M (P25,P75)]

pg/ml

1.4 (0.8, 1.8)

1.3 (0.8, 1.7)

1.3 (0.8, 1.7)

0.9 (0.8, 1.5)

0.11

IL-12p70 [M (P25,P75)]

pg/ml

1.8 (1.0, 3.5)

1.6 (1.0, 2.6)

1.7 (0.8, 2.5)

1.4 (0.9, 2.0)

0.20

IL-17 [M (P25,P75)]

pg/ml

1.6 (1.1, 2.8)

1.6 (1.1, 3.1)

1.5 (0.9, 2.4)

1.3 (1.1, 1.9)

0.52

IFN-α [M (P25,P75)]

pg/ml

1.9 (1.0, 4.9)

1.6 (0.9, 4.5)

1.5 (0.8, 4.3)

1.2 (1.1, 1.5)

0.14

IFN-γ [M (P25,P75)]

pg/ml

7.1 (3.7, 10.8)

2.9 (1.6, 5.5)

3.1 (1.2, 5.6)

2.5 (1.3, 3.6)

< 0.0001

TNF-α [M (P25,P75)]

pg/ml

2.4 (1.5, 3.9)

2.3 (1.1, 3.9)

2.3 (1.2, 4.7)

2.1 (1.3, 2.5)

0.34