Fig. 3
From: Malignant mesothelioma-associated inflammatory microenvironment promotes tumor progression via GPNMB

Effects of GPNMB on the growth of murine MPM cells in vitro. A ELISA of GPNMB in Mock and GPNMB-transduced AB1 and AB22 cells. B In vitro proliferation of Mock and GPNMB-transduced cells. C In vitro sphere formation of Mock and GPNMB-transduced tumors cells from AB1 and AB22 cell lines. D Quantification of spheres and phenotype analysis for stem cell markers in adherent Mock-AB1 cells (adh) and in dissociated spheres from GPNMB-AB22 cells (sph). E Same as in D for AB22 cells. Statistical analysis Two-way ANOVA for B, **** p < 0.01, Student t-test, Welch’s correction for D and E