Fig. 1
LysoPS promotes GPR174 expression and is correlated with ESCC invasion and metastasis. A LC–MS analysis revealed the concentrations of LysoPS (18:0) and LysoPS (18:1) in ESCC tissues. (n = 26) B Proliferation of TE-12 and TE-1 cells treated with 10 μM LysoPS (18:1) for 24, 48, 72, and 96 h. C, D Expression and statistical analysis of GPR174 in TE-1 and TE-12 cells after 1 day of treatment with 10 μM LysoPS (18:1). E Cell migration of TE-12 cells assessed by scratch assay following 12 h of treatment with 10 μM LysoPS (18:1), along with its statistical analysis. Scale bars, 200 μm. F An assessment of cell invasion and migration in TE-1 and TE-12 cells after 48 h of treatment with 10 μM LysoPS (18:1) using the Transwell assay, along with corresponding statistical analyses. Scale bars, 100 μm