Fig. 2

High levels of GPR174 in cancer tissues are associated with a poor prognosis. A An illustrative IHC image depicting GPR174 expression in ESCC tissue, with scale bars indicating 200 μm and 20 μm. B A statistical evaluation of GPR174 expression in cancerous versus adjacent non-cancerous tissues, derived from IHC data of 74 ESCC patients. C, D A statistical assessment of GPR174 expression in cancerous tissues from a cohort of 98 ESCC patients, utilizing IHC results of TMA. E Kaplan–Meier survival analysis of 98 patients with ESCC presenting high or low GPR174 expression