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Table 1 Correlation between GPR174 protein expression and clinicopathological features of 98 patients with esophageal squamous cell carcinoma

From: The LysoPS/GPR174 axis drives metastatic progression in esophageal squamous cell carcinoma through cAMP-PKA-CREB signaling activation

Clinicopathological variables

n

GPR174 expression

P valuea

Low

High

Age

   

0.102

 < 60

30

8

22

 

 ≥ 60

68

30

38

 

Gender

   

0.638

 Female

15

5

10

 

 Male

83

33

50

 

Tumor Size

   

0.290

 < 5 cm

58

25

33

 

 ≥ 5 cm

40

13

27

 

Differentiation

   

0.478

 Well and moderate

71

26

45

 

 Poorly and not

27

12

15

 

TNM stagesb

   

< 0.0001*

 I–II

38

24

14

 

 III–IV

60

14

46

 

Tumor invasion

   

0.071

 T1–T2

13

8

5

 

 T3–T4

85

30

55

 

Lymphatic invasion

   

< 0.001*

 N0

39

23

16

 

 N1–N3

59

15

44

 
  1. aAll P values were determined by chi-square test; bTNM staging was AJCC 7th edition staging