Fig. 6

Bulk RNA sequencing analysis for biological basis associated with the RF-habitat radiomics model. (A) Heatmap depicted the expression profiles of DEGs between low and high-risk groups stratified by the RF-habitat radiomics model. (B) Volcano plot showed the distribution of DEGs between two groups. (C) KEGG enrichment barplot displayed the key pathways enriched by DEGs. (D) GSEA based on the Gene Ontology (GO) database revealed immune and metabolism-related pathways enriched in the high-risk group